TITEL
Combining a resonance and a Raman sensor, towards a new method for localizing prostate tumors in vivo
FöRFATTARE
Candefjord, Stefan
INSTITUTION
Systemteknik / Medieteknik
SAMMANFATTNING
Prostate cancer is the most common malignancy diagnosed in western men today.
Measuring the amount of prostate-specific antigen in blood is the most
widespread tool for diagnosing prostate cancer early on. However, clinical
investigations show that many people with high levels of PSA can be healthy
and vice versa. Ultrasound-guided biopsies is the clinical method used to
prove prostate cancer. Unfortunately, many tumors are overlooked by this
procedure. It has been estimated that about 30% of the biopsy examinations
fail to find a present tumor. The resonance technique, which can
differentiate hard and soft materials, has in vitro been shown to be able to
distinguish prostate cancer and healthy epithelial prostate tissue. Raman
spectroscopy is also a good candidate for detecting prostate cancer. Our
novel idea of combining the resonance and Raman techniques into a portable
probe, appropriate for in vivo examinations of the prostate, will be
discussed in this report. The two techniques are presented and explained, and
the feasibility of combining them is discussed. Planned experiments and
investigations are outlined.
ISSN 1402-1536 / ISRN LTU-TR--07/15--SE / NR 2007:15
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